Ray of Hope

 

 

 

Alzheimer’s disease patients are in need of constant and extensive care as they slowly lose control over different functional and mental abilities. They are incapable of taking care of themselves. Loss of such abilities affects patients and family members or other caregivers. Although one main cause for Alzheimer’s disease is deposits of amyloid protein, such deposits alone are not responsible for all the severe symptoms of Alzheimer’s disease. But, treating the causes of amyloid deposits could lower the incidence of Alzheimer’s disease.

 

 

New Treatment Options

 

Amyloid Precursor Proteins and other associated substances are responsible for major dysfunction in the abilities of the brain. Therefore, new treatments hint at two major options for Alzheimer’s disease. The first option is to create amyloid antigen by injecting beta amyloid protein to create antibodies. These beta amyloid antibodies could delay the onset of Alzheimer’s disease. The second option is to develop immunity therapy through amyloid beta antibodies and not through protein antibodies. Although high dosages of such antibodies were necessary for effective treatment in the tests, side effects were inflammation and hemorrhage. Since the second option was fatal, scientists are trying to modify the first option. Injection of amyloid protein antibodies causes meningoenchaphalitis due to autoimmune activation of T-cells. One viable solution could be to develop vaccines to lessen T-cell activation to a minimum and at
same time produce amyloid beta (Aß) antibodies.

 

 

Experiments on mice indicate positive results. Besides, reduction of side effects is possible by injecting antibodies directly into the brain instead of into the body. Such injection into the brain necessitates smaller dosages of antibodies and produce a sharp fall in side effects. All scientific experiments have been on mice and scientists are trying to learn the effectiveness of such treatments on humans with Alzheimer’s disease. This does offer a ray of hope for all patients and their family members, although scientific conclusions are still in a very fluid stage.

 

 

There are also plans to develop extremely sensitive and refined research tools to aid in more complicated and extensive experiments. There have been extensive studies and, though scientists do not know all the causes of A.D., their have been several things learned which they try and believe do help:

 

Sunlight:

 

Getting enough sunlight and keeping on a regular sleeping pattern, where they sleep at night and are awake in the daytime. (All people need sunlight!)

 

Vitamin B Therapy:

 

In 1994, McCaddon noted that AD patients lack folic acid. Later, another scientist (Snowden in 2000) discovered that AD patients were low in B-12. (Low B-12 is common in older people as it is not absorbed well.) Other possibilities are getting antioxidants to help fight free radicals, and keeping the blood circulating well. You must discuss these things with the doctor of the AD patient, and it is not a good idea to start doing everything all at once for these reasons:

 

  • If one thing does work, then you’d be spending money on other therapies that are not needed.
  • It is best to not over tax a patient’s system with additives.
  • Some therapies cause the blood to thin, and you need to be especially careful of bleeding.
  • Make sure your loved one gets care and attention, proper vitamins and nutrition.